Gold Key #235 - September 1976
From Toonopedia...
Little Lulu was created by Marjorie Henderson Buell ("Marge"), who used her in a series of single-panel cartoons. These were commissioned by The Saturday Evening Post to replace Carl Anderson's Henry, which had been picked up by King Features, and ran from Feb. 23, 1935 to 1948. It took Lulu almost a decade to transcend that venue, but when she did, she did it all over the place — by the mid-1940s, she was a star of comic books and animated cartoons, as well as the spokestoon for Kleenex.
It was in comic books that Lulu truly found her place. The first issue of Marge's Little Lulu appeared in 1945 from Dell Comics. In a popular series within the series, Lulu told stories to her younger neighbor, Alvin, about a poor little girl who picked beebleberries in the woods, and had adventures with Witch Hazel and Little Itch. Marge's Little Lulu was published regularly until 1984. In 1972, it underwent a name change. Western Publishing, which at that time was publishing the comic under its Gold Key imprint, solved the royalties problem in a more healthy way than Famous Studios had — they bought the character from Buell, and thereupon dropped "Marge's" from the title.
This is Little Lulu #235 - September 1976