Harvey Comics #229 February 1987
From Toonopedia...
Casper first appeared in a cartoon entitled (appropriately enough) The Friendly Ghost, based on an unpublished story written by Seymour V. Reit The cartoon was directed by Isadore Sparber and released by Paramount's Famous Studios, as part of its "Noveltoons" series, in 1945. This sentimental tale of a ghost who didn't want to scare anyone was well enough received to spark a sequel, There's Good Boos Tonight (1948), also directed by Sparber.
This led to a full-blown series, some directed by Sparber and some by Seymour Kneitel. During the 1950s, Casper cartoons, which all had more-or-less the same plot, followed one upon another with monotonous regularity, outlasting all his Famous Studios contemporaries except Herman & Katnip. The last theatrically-released Casper cartoon was Casper's Birthday Party, released July 31, 1959 and directed by Kneitel.
In 1949, Casper became a comic book character, when St. John Publishing secured the rights to do all of Paramount's cartoon characters in that venue. In 1952, the license was transferred to Harvey Comics, which bought the characters outright in the late 1950s — they were published regularly until 1982, and sporadically since.
This issue #229 published in October 1986 was the fourth of a re-issue of the series that lasted up to issue 253 in 1990 when the title was changed to Casper, the Friendly Ghost. The previous title had not been used since #228 in 1958.